Scientists from the California Technological Institute (CALTECH) have developed micro-robots designed to move within the body, deliver medicines accurately, and then dissolve harmlessly. These microbots are spherical structures made from hydrogel, a material commonly found in items such as contact lenses.
This innovative invention allows for the precise targeting of robots to specific areas of the body using an external magnetic field. Magnetic nanoparticles contained within the robots enable researchers to control their movement. Once the designated target is reached, the microbots begin slowly releasing medicine, ensuring a controlled and effective delivery process.
To facilitate movement, scientists outfitted the microbots with tiny “shoes” containing two holes. When exposed to ultrasound, the bubbles within the shoes vibrate, pushing liquid through the holes and propelling the robots forward. This technology also enables real-time monitoring of the microbots’ movement, utilizing the bubbles as a contrast agent for ultrasound imaging.
Initial experiments with mice have demonstrated the high efficacy of this technology. Microbots successfully delivered drugs, resulting in a reduction in the size of bladder tumors. The next phase will involve clinical trials to validate the potential use of microbots in treating a range of diseases.
Professor of medical engineering Wei Gao emphasized the groundbreaking nature of this platform, highlighting its capability for precise drug delivery and potential for use in surgical procedures. The long-term goal is for this development to serve as the foundation for treating various medical conditions using diverse therapeutic agents.