Researchers from the University of Science and Suul’s technology have developed innovative biocarriers based on nanocellulose obtained from tea fungus (Kombucha Scoby). This biomaterial can be used for 3D bioprinting of living cells in damaged areas of tissues, opening up new opportunities in regenerative medicine.
The Biocherial, created by scientists, are designed for use with a digital Biowork bioprinter, which allows cells to be applied directly to damaged areas, including complex wounds and cartilage defects. This technology has the potential to replace traditional methods of tissue growth in the laboratory, speeding up the healing process and making treatment more affordable.
The main component of the Bio-CHICH is nanocellulose obtained from tea fungus. During the research, scientists partially hydrolyzed it with acetic acid to improve the material’s fluidity and suitability for bioprinting. However, this process weakened the structure, so the nanocellulose was further reinforced with nanoparticles of chitosan and kaolin, creating a stable hydrogel.
When using the bio-hand, the components of the bio-carrier, including living cells, are mixed in the device using two rotating screws. This ensures the uniformity of the composition and allows the material to be applied directly to damaged tissues, forming multi-layer and self-supporting structures. The technology has also shown effectiveness in filling complex defects, such as models of the skull and femoral head.
The development promises to be an inexpensive and convenient solution for emergency medical care, enabling the swift restoration of damaged tissues without the need to grow cells in laboratory conditions.