Researchers from the Royal College of London, the University of Exterus, and the University of California at Irvain revealed the critical role of the KDM5B gene in the management of learning and memory processes. The study, published in the Journal of Neuroscience, found that mice with reduced function of this gene experienced significant disorders in their ability to learn and memorize.
The KDM5B gene is essential for strengthening neuronal connections, which are crucial for memory formation. The research confirms that altering the activity of this gene directly impacts the ability to learn and retain information, making it a significant area of study in relation to intellectual disorders and autism.
Professor Albert Basson, leading the research group, commented, “The ability to learn and remember is fundamental to our intellectual capacity, and there is still much to uncover about the mechanisms underlying these processes.” The study commenced at the Royal College of London and continued at the University of Exterpers.
Through experiments, it was discovered that KDM5B can alter the structure of genetic material, influencing the expression of genes necessary for brain development. Dr. Letizia Perezisez, the study’s lead researcher, stated, “Our research aimed to investigate the direct impact of KDM5B on learning and memory by modifying genetic material. We found that this gene has a unique effect on these processes, distinct from its role in brain development.”
These findings have the potential to lead to new treatment approaches for individuals with intellectual disorders and autism.