A vast study, published on Tuesday by Epi-Phare, confirms the safety of Moderna and Pfizer vaccines, while highlighting a surrecound with vaccines in Adenovirus.
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A new study confirms the safety of RNA messenger vaccines vis-à-vis the risk of serious cardiovascular events in adults under 75 years of age. According to a vast study published Tuesday, January 18th on the site of Epi-Phare , a group of scientists from the National Safety Agency of the Drug and Medicare, these vaccines do not are not associated with a risk of acute myocardial infarction, stroke (stroke) or pulmonary embolism, during the three weeks of each of the first two doses.
On the other hand, vaccines in Adenovirus of Astrazeneca and Janssen “appear associated with a slight increased risk of myocardial infarction and pulmonary embolism” among children under 75, write the authors. Results that validate the vaccine strategy put in place for several months in France, since now, only RNA Messenger vaccines in Pfizer / Biontech and Modera are offered as part of the VVID-19 vaccination campaign. Since the summer of 2021, adenovirus vaccines have been systematically given to the COVAX program and sent to countries that do not have or few vaccines.
“It’s a major result. At the international level, there have already been work that went in this direction, but this study is interesting because it relates to a very large number of subjects, that is to- To say all the people who had this type of event in France between December 27, 2020 and July 20, 2021, “says Rosemary Dray-Spira, Deputy Director of EPI-Phare, who oversaw the study.
No surpris
These works are indeed on more than 46 million French aged 18 to 74, including all individuals with severe cardiovascular event with hospitalization over the period were included. This completes The work already published in November 2021 by the same team in the journal Journal of the American Medical Association for more than 75 years, for which no acute myocardial infarction, stroke or pulmonary embolism was not detected in the short term afterwards. A vaccination with Pfizer.
The method used, “self-terrified case series”, also makes it possible to avoid certain biases encountered in actual lives. “With this methodology, we compare every subject to itself, before and after vaccine injection,” says Rosemary Dray-Spira:
“This allows us to free ourselves from the limits of observational studies for which there are difficulties in comparing two groups of different people.”
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