Halle York Medical School and the Faculty of Mathematics of York University identified unique markers in the blood of patients with COVID-19, which make it possible to prevent the serious course of the disease and fatal outcomes. This is reported in an article published in the archive of preprints of ISCience.
Researchers tested blood samples of more than 160 patients hospitalized during the first and second pandemic wave. Levels of 25 cytokines and chemokines – proteins in the blood, which regulate the immune response were measured. Also, scientists also estimated the level of 171 microns, which reflects the degree of damage to coronavirus tissue.
It turned out that the combination of micrograph and proteins makes it more accurate to distinguish the difficult cases of COVID-19 than the measurement of the levels of these factors separately. At the same time, the CCL20 chemocin, IL6 and IL10 interleukins and IL10, as well as the MIR-451 micrograph were key indicators of the fatal outcome of the coronavirus infection.