California University scientists found out that many experiments that were considered as promising achievements and became the basis for finding drugs from cancer are not reproduced. Of the serunted selected scientific experiments, about half failed to confirm. This is reported in a press release on MedicalXpress.
In the framework of the project, experts tried to reproduce research that were published in major scientific publications, such as Cell, Science and Nature, in 2010-2012. It turned out that 54 percent of the results did not comply with the statistical criteria of reproducibility.
For example, among studies that failed to confirm, there was a work that showed that certain intestinal bacteria are associated with colon cancer in humans. Another article was devoted to a drug that reduces breast tumor in mice.
It is worth noting that the reproducibility criteria also did not correspond to the test results on the mice of potential medication from prostate cancer. However, the authors of the work claim that it was confirmed by other scientific groups, and the compound is currently undergoing a clinical study in humans. In addition, the results of testing of reproducibility are criticized only the first stages of searching for cancer treatment methods, and not existing treatments.