The international team of researchers came to the conclusion that in terms of expression of the so-called flower protein, it is enough to precisely predict the outcome of a coronavirus infection – whether death or hospitalization is in a person. The relevant article dedicated to the found by scientists in the prediction of the COVID-19 flow, published in the EMBO Molecular Medicine magazine.
Low status of the cell adaptability indicates that it is not well developed enough – either because of its aging, or due to violations in metabolism and so on. Scientists have found that the status of adaptability is expressed in FWE proteins. They are located on the cell surface and are expressed in two forms – one says that the cell feels good, and the “owners” are destroyed by surrounding cells.
Scientists from Great Britain, Germany, Denmark, Portugal and the United States conducted a pathoanomatic study of fabrics infected with coronavirus of the lungs of the dead from COVID-19 patients. It turned out that patients with acute damage to the lungs fwe-lose in the lower respiratory tract was expressed extremely strongly and was localized in the fields of cellular necrosis.
The specialists then conducted a observative study of 283 people in order to determine if the expression of the FWE protein can predict hospitalization or death at COVID-19. “The method allows you to determine who needs hospitalization with accuracy of 87.8 percent. Accuracy of the prediction of patients who do not develop a hard form of COVID-19, amounted to 93.9 percent,” says one of the authors of the study, Associate Professor of Copenhagen University of Ken Jeavon ( Kyoung Jae Won). Accuracy of the prediction of deadly outcomes can reach 100 percent. The researchers emphasize that in terms of expression of the FWE protein, the outcome of the disease can be predicted better than according to traditional inflammatory biomarkers.