Researchers from the United States have shown that according to markers of Methylization of human DNA, it is possible to determine not only the presence of COVID-19, but also to predict how hard it can flow from him. The article of scientists in which they offer a new testing method for the presence of coronavirus infection, published in Communications Medicine magazine.
Most express tests and tests for antibodies to COVID-19 are high levels of false negative results. In addition, it is impossible to say whether the virus is replicated, and what will be the outcome of the disease. The decision, according to researchers from the Colorado University, may be an analysis of markers associated with DNA methylation – a process in which the molecule is modified without changing the nucleotide sequence.
Scientists have collected peripheral blood samples in 164 patients with COVID-19 and 296 healthy people who served as a control group. According to the results of the analysis of Epigenome, researchers managed to find genetic markers specific to SARS-COV-2, as well as markers for which the severity of the disease can be assumed. Experts emphasize that the latter were present in the blood of patients already at the first blood fence.