Researchers from Germany found biomarkers in human blood, the increased content of which may indicate the Sorrow of Lyubami. The article of scientists is published in the magazine EMBO Molecular Medicine.
German specialists led by researchers from Göttingen and Munich universities decided to find out whether the content of certain microns – molecules involved in the regulation of protein production – with the development of dementia in the future. For this, scientists conducted research on mice and in cell cultures, and also analyzed the blood showed good results during the cognitive tests of volunteers.
As a result, they managed to identify three microns, the level of content of which correlated with intellectual abilities. After that, the researchers compared the data on the content of the micrograph in the blood of healthy young people and in elderly patients with moderate cognitive disorders. The lower the level of their blood content in healthy people, the better the results they demonstrated during the cognitive texts. In 90 percent of patients with moderate cognitive impairments that have increased their level, Alzheimer’s disease has developed for two years.
This correlation was confirmed and at mice – at the same time, the increase in the level of the content of three microns could be recorded long before the reduction of cognitive abilities. According to scientists estimates, the presence of these markers signals the development of dementia in a person in two or five years.
Researchers found out that all three microgs affect inflammatory processes in the brain and on neuroplasticity – the ability of neurons to establish links among themselves. “In our opinion, they are not only markers, but also actively affect the pathological processes, which makes them potential targets for therapy,” said the head of the scientific group, Professor of Göttingen University Andre Fisher.