Researchers from the United States have shown that at the surveillance of COVID-19 people and in the coronavirus infection have been distinguished from the work of B-lymphocytes. The article of scientists was accepted for publication in the journal Nature.
The content of antibodies in time inevitably falls – which increases the risk of re-infection. At this case, the body has a “spare plan”: in-cells of memory – in lymphocytes that allow the immunity to “remember” the antigen over the years and during its penetration to quickly respond to the development of a large number of antibodies.
Researchers from Rockefeller University compared blood samples obtained from patient coronavirus infection and from 32 people who received two doses of different MRNA-Vaccines – Moderna and Pfizer – and previously not infected. In both cases, scientists revealed the same amount of memory b-cells.
between the first and second dose of the B-lymphocyte vaccine actively evolved and produced increasingly strong antibodies. However, after two months, the process stopped – antibodies did not become stronger. Despite the fact that some of them could neutralize the “delta” -variant and other new variants of coronavirus, the latitude of their neutralization was not expanding. In the overwhelmed patients of B-cell memory continued to evolve and produce increasingly powerful antibodies of an increasingly wide range of action and after a year.
The reason for this phenomenon, scientists note, may be the different reaction of the body to penetrate the virus through the respiratory tract or through the limb vessels. There is a possibility that the long-term presence of virus particles in the body throughout the infection.