Russian researchers studied stem cells involved in wound healing. They disclosed that in the layer of multipotent mesenchymal stromal stem cells (MMSK) there are areas where cells are differently different. The opening is reported on the RHF website.
MMSK can turn into bone tissue cells (osteoblasts), cartilage cells (chondrocytes) and fat tissue cells (adipocytes). When the wound healing process is activated, stem cells are chosen in what type of mature cells they need to be transformed. This is affected by the stroma – the accumulation of connective tissue, playing a structural and supporting role for internal organs.
To determine the mechanisms of regeneration, scientists experimented with MMSC of human adhesive tissue. They grown plars from stem cells in a special environment to trace what exactly they would be differentiated. It turned out that at the same time, sectors were formed in the formations with a high concentration of stem cells that turn into cells of bone and cartilage tissues. In addition, the fat cells were not formed, because in MMSC, genes were active, overwhelming this transformation.
According to scientists, the results that shed light on the regeneration mechanisms will help to develop methods in the future to heal wounds without scars.