Canadian researchers have shown that concern new SARS-COV-2 versions have greater virulence than the original “Wuhan”. The article of scientists has been published in Canadian Medical Association Journal.
Specialists from the University of Toronto rated more than 212 cases of coronavirus infection, recorded from February to June 2021 in the province of Ontario. 76 percent of the illness infected “alpha”, “beta” and “gamma” -rentions associated with the N501Y mutation in the coronavirus S-protein, which increases its transmission. 2.8 percent infected “Delta” -Var.
It was found that such people were, as a rule, younger and they were less likely to have concomitant diseases compared to those who have become infected with other options. When “Alfa”, “Beta” and “Gamma” -variants, the risk of hospitalization of patients was higher by 52 percent. The risk of getting into the resuscitation department is 89 percent, die – by 51. For the “delta” -variant, these indicators were 108, 235 and 133 percent, respectively.
In addition, researchers analyzed the effect provided by vaccination. “The effects shown here indicate a significant degree of protection of vaccines from death (about 80-90 percent), even if their receipt did not prevent infection,” the authors noted in their work. According to researchers, the increased virulence of SARS-COV-2 variants, causing concern, will lead to a significantly greater scope of the coronavirus pandemic.
The fact that the large contagiousness of the “Alpha” -Variant of Coronavirus explains the N501Y mutation, installed researchers from Spain in February. The mutant version of the S-protein has increased affinity for binding with the receptor HACE-2 – the main “gates” for coronavirus into the cell.