University of Massey (New Zealand) discovered that the high activity of the gene encoding the protein to form new blood vessels may prevent the healing of the damaged heart and interfere with the long survival of patients after a patient suffered. About a new way to predict death from a heartfelt violation is reported in an article published in the PLOS One.
1927 patients took part in the study, 30 percent of which were not the first episode of a serious heart disease. Experts analyzed the VEGF-A gene and tied various options with survival after an attack.
Scientists assumed that high levels of VEGF-A may be useful for the growth of new blood vessels around the clogged arteries. However, studies carried out so far contradict the hypothesis that a large amount of VEGF-A protein in the bloodstream is associated with the best outcome in heart disease.
In the new work, it was demonstrated that the high levels of VEGF-a may indicate the body’s attempt to restore the heart function, which is not always possible with strong damage. The probability of death of patients with high VEGF-A for eight years after initial hospitalization is more than 40 percent than low protein patients.