Canadian researchers in mice experiments have shown that the nutritional limit may be useful for the body when developing bacterial infections in it. The work of scientists was published in the PLOS PATHOGENS magazine.
The loss of appetite is a widespread symptom of infectious diseases. However, it is unclear whether the starvation is protected when combating infections, or, on the contrary, increases the exposure to them.
In his new study, scientists from the University of British Columbia made mice hungry for 48 hours before and before infection of the Salmonella Enterica bacteria – one of the main pathogens of Salmonelleza. It turned out that the symptoms of infection were significantly reduced in comparison with the “satisted”, in particular, inflammation and damage to the bowel tissues were practically disappeared. When such experimental fed, it turned out that the number of salmonell in their body increased dramatically. Similar results were observed in experiments with Campylobacter Jejuni bacteria. At the same time, nastobiotic (grown in a completely sterile setting) Fasting mice did not affect the spread of Salmonelle – what can say that its effect is explained by the influence on the microbis of the body.
According to scientists, their research shows that therapeutic starvation or calorie limit of food can afford to fight infectious (A, possibly with non-infectious) intestinal diseases.