American scientists from the Scripps Institute found out that the means from worms can become a promising medicine from COVID-19. The results of the study are published in the ACS Infectious Disease magazine.
Salicylanilides were able to prevent coronavirus infection to penetrate the cells, as well as fight the cytokine storm. Most likely, Salicylanilide will cope with new COVID-19 mutations. However, it has not been tested on people. “For 10-15 years, it is known that salicylanilides are effective against certain viruses. However, the zone of action is usually limited to the intestine, and the drugs may be toxic,” the lead author of Kim Janda study explained.
When Coronavirus began to spread, Janda decided to find out how much salicylanilides will be effective against SARS-COV-2. One of the compounds during the study turned out to be the most efficient. It hurt the infection of cell cultures. The compound reduced the level of interleukin-6, signal protein, which is known as the key inflammation factor, usually observed in the later stages of COVID-19.
Previously, scientists from the Medical University of South Carolina reported that the level of serum in the serum of the aminopirt of Sfingosin could predict in what form the patient suffers a coronavirus infection. Specialists checked about 400 samples of the serum of healthy people and patients who in varying severity sorted COVID-19. They found out that the increased concentrations of Sphingosin, as well as a protein, which participates in its production, acidic ceramidase (AC), are associated with asymptomatic infections.